Cytosolic and mitochondrial glutathione oxidoreductase; converts oxidized glutathione to reduced glutathione; cytosolic Glr1p is the main determinant of the glutathione redox state of the mitochondrial intermembrane space; mitochondrial Glr1p has a role in resistance to hyperoxia; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000006012]
LPG17
Chromosome XVI: 375,502-376,953 forward strand.
R64-1-1:BK006949.2
This gene has 1 transcript (splice variant), 334 orthologues, 4 paralogues and is a member of 1 Ensembl protein family.