Protein involved in regulation of sterol biosynthesis; specifically stabilizes Hmg2p, one of two HMG-CoA isoenzymes that catalyze the rate-limiting step in sterol biosynthesis; homolog of mammalian INSIG proteins; NSG2 has a paralog, NSG1, that arose from the whole genome duplication [Source:SGD;Acc:S000005100]
Chromosome XIV: 341,069-341,968 reverse strand.
R64-1-1:BK006947.3
This gene has 1 transcript (splice variant), 200 orthologues, 1 paralogue and is a member of 1 Ensembl protein family.