Transcriptional regulator; facilitates elongation through factors that modify RNAP II; role in peroxide resistance involving Rad2p; role in nonhomologous end-joining (NHEJ) of ds breaks in plasmid DNA, but not chromosomal DNA; role in the hyperosmotic stress response through polymerase recruitment at RNAP II and RNAP III genes; negatively regulates sporulation; protein abundance increases in response to DNA replication stress; functionally complemented by human SUB1 (PC4) [Source:SGD;Acc:S000004642]

TSP1

Chromosome XIII: 348,644-349,522 reverse strand.

R64-1-1:BK006946.2

This gene has 1 transcript (splice variant), 56 orthologues and is a member of 1 Ensembl protein family.

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