Protein involved in silencing at mating-type loci HML and HMR; recruitment to silent chromatin requires interactions with Orc1p and with Sir4p, through a common Sir1p domain; binds to centromeric chromatin [Source:SGD;Acc:S000001809]
Chromosome XI: 640,540-642,504 forward strand.
R64-1-1:BK006944.2
This gene has 1 transcript (splice variant) and 6 orthologues.
Name | Transcript ID | bp | Protein | Translation ID | Biotype | UniProt | RefSeq | Flags |
---|---|---|---|---|---|---|---|---|
SIR1 | YKR101W_mRNA | 1965 | 654aa | YKR101W | Protein coding | P21691 | - | Ensembl Canonical, |