Endonuclease involved in pre-rRNA processing at both ends of ITS2; functions with Grc3p in a conserved mechanism to modulate rRNA processing and ribosome biogenesis; may coordinate the action of the Rat1p-Rai1p exoRNAse; required for the G1/S cell cycle transition; human ortholog is Las1L; mutants require the SSD1-v allele for viability [Source:SGD;Acc:S000001771]

Chromosome XI: 560,789-562,297 reverse strand.

R64-1-1:BK006944.2

This gene has 1 transcript (splice variant), 305 orthologues and is a member of 1 Ensembl protein family.

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