Peptidylprolyl-cis/trans-isomerase (PPIase); specific for phosphorylated S/T residues N-terminal to proline; regulates phosphorylation of RNAPII large subunit (Rpo21p) C-terminal domain (CTD) at Ser7; associates with phospho-Ser5 form of RNAPII in vivo; present along entire coding length of genes; represses initiation of CUTs; required for efficient termination of mRNA transcription, trimethylation of histone H3; human ortholog PIN1 can complement yeast null and ts mutants [Source:SGD;Acc:S000003778]

PIN1, PTF1

Chromosome X: 466,521-467,033 reverse strand.

R64-1-1:BK006943.2

This gene has 1 transcript (splice variant), 342 orthologues and is a member of 1 Ensembl protein family.

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