Subunit of RNase MRP, nuclear RNase P and telomerase; forms a soluble heterodimer with Pop7p that binds P3 domain of RNase MRP and RNase P RNAs; RNase MRP cleaves pre-rRNA, nuclear RNase P cleaves tRNA precursors to generate mature 5' ends and facilitates turnover of nuclear RNAs, while telomerase replenishes telomeric DNA; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000003262]

Chromosome VII: 545,681-546,157 reverse strand.

R64-1-1:BK006941.2

This gene has 1 transcript (splice variant) and 16 orthologues.

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