Methylglyoxalase that converts methylglyoxal to D-lactate; involved in oxidative stress resistance, diauxic shift, and stationary phase survival; has similarity to E. coli Hsp31 and C. albicans Glx3p; member of the DJ-1/ThiJ/PfpI superfamily, which includes human DJ-1 involved in Parkinson's disease and cancer; exists as a dimer and contains a putative metal-binding site; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000002941]
Chromosome IV: 1,501,447-1,502,160 reverse strand.
R64-1-1:BK006938.2
This gene has 1 transcript (splice variant), 360 orthologues, 3 paralogues and is a member of 1 Ensembl protein family.
Name | Transcript ID | bp | Protein | Translation ID | Biotype | UniProt | RefSeq | Flags |
---|---|---|---|---|---|---|---|---|
HSP31 | YDR533C_mRNA | 714 | 237aa | YDR533C | Protein coding | Q04432 | - | Ensembl Canonical, |