Highly conserved negative regulator of RNA polymerase III; involved in tRNA processing and stability; inhibits tRNA degradation via rapid tRNA decay (RTD) pathway; binds N-terminal domain of Rpc160p subunit of Pol III to prevent closed-complex formation; regulated by phosphorylation mediated by TORC1, protein kinase A, Sch9p, casein kinase 2; localizes to cytoplasm during vegetative growth and translocates to nucleus and nucleolus under stress conditions [Source:SGD;Acc:S000002412]

Chromosome IV: 456,836-458,103 reverse strand.

R64-1-1:BK006938.2

This gene has 1 transcript (splice variant), 341 orthologues and is a member of 1 Ensembl protein family.

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