Cytoplasmic DEAD-box helicase, stimulates mRNA decapping; coordinates distinct steps in mRNA function and decay, interacting with both decapping and deadenylase complexes; role in translational repression, mRNA decay, and possibly mRNA export; interacts and cooperates with Ngr1p to promote specific mRNA decay; ATP- and RNA-bound form promotes processing body (PB) assembly, while ATPase stimulation by Not1p promotes PB disassembly; forms cytoplasmic foci on replication stress [Source:SGD;Acc:S000002319]

Chromosome IV: 170,410-171,930 reverse strand.

R64-1-1:BK006938.2

This gene has 1 transcript (splice variant), 375 orthologues, 26 paralogues and is a member of 1 Ensembl protein family.

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