Cyclin-dependent protein kinase regulatory subunit and adaptor; interacts with Cdc28p (aka Cdk1p); required for G1/S and G2/M phase transitions and budding; mediates phosphorylation and degradation of Sic1p; modulates proteolysis of M-phase targets through interactions with the proteasome; role in transcriptional regulation, recruiting proteasomal subunits to target gene promoters; human homologs CKS1B and CKS2 can each complement yeast cks1 null mutant [Source:SGD;Acc:S000000339]
Chromosome II: 504,854-505,306 forward strand.
R64-1-1:BK006936.2
This gene has 1 transcript (splice variant), 221 orthologues, 1 paralogue and is a member of 1 Ensembl protein family.
Name | Transcript ID | bp | Protein | Translation ID | Biotype | UniProt | RefSeq | Flags |
---|---|---|---|---|---|---|---|---|
CKS1 | YBR135W_mRNA | 453 | 150aa | YBR135W | Protein coding | P20486 | - | Ensembl Canonical, |