Subunit B of V1 peripheral membrane domain of vacuolar H+-ATPase; electrogenic proton pump found throughout the endomembrane system; contains nucleotide binding sites; also detected in the cytoplasm; protein abundance increases in response to DNA replication stress; human homolog ATP6V1B1, implicated in autosomal-recessive distal renal tubular acidosis (RTA) with sensorineural deafness, complements yeast null mutant [Source:SGD;Acc:S000000331]

ATPSV, VAT2

Chromosome II: 491,269-492,822 reverse strand.

R64-1-1:BK006936.2

This gene has 1 transcript (splice variant), 372 orthologues, 3 paralogues and is a member of 2 Ensembl protein families.

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