Pyruvate kinase; functions as a homotetramer in glycolysis to convert phosphoenolpyruvate to pyruvate, the input for aerobic (TCA cycle) or anaerobic (glucose fermentation) respiration; regulated via allosteric activation by fructose bisphosphate; CDC19 has a paralog, PYK2, that arose from the whole genome duplication [Source:SGD;Acc:S000000036]

PYK1

Chromosome I: 71,786-73,288 forward strand.

R64-1-1:BK006935.2

This gene has 1 transcript (splice variant), 405 orthologues, 1 paralogue and is a member of 1 Ensembl protein family.

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