Cryptococcus neoformans var. neoformans JEC21 Assembly and Gene Annotation

About Cryptococcus neoformans var. neoformans JEC21

Cryptococcus neoformans is an encapsulated basidiomycetous yeast belonging to the class Tremellomycetes and an obligate aerobe that can live in both plants and animals. Its teleomorph is a filamentous fungus, formerly referred to Filobasidiella neoformans. In its yeast state, it is often found in bird excrement. It has remarkable genomic plasticity and genetic variability between its strains, making treatment of the disease it causes difficult. Cryptococcus neoformans causes disease primarily in immunocompromised hosts, such as HIV or cancer patients. In addition it has been shown to cause disease in apparently immunocompetent hosts, especially in developed countries.

Picture credit: Public domain via Wikimedia Commons (Image source) Taxonomy ID 214684

(Text from Wikipedia.)

More information General information about this species can be found in Wikipedia

Assembly

The Institute for Genomic Research (TIGR)](http://www.tigr.org/tdb/e2k1/cna1/), in collaboration with Stanford University, sequenced the Cryptococcus neoformans var. neoformans strain JEC21 (serotype D) genome at approximately 12.5X coverage using whole genome shotgun (WGS) sequencing. TIGR produced the genome assembly, which integrates the WGS sequence data from TIGR and Stanford University with closure reads from TIGR and BAC end sequences from the Genome Sciences Centre and Dr. Jim Kronstad, University of British Columbia. The sequencing and assembly of the Cryptococcus neoformans JEC21 genome is complete. The assembly has been loaded from the 14 chromosomes deposited in INSDC as GCA_000091045.

Annotation

The Institute for Genomic Research (TIGR) has annotated over 6,500 predicted protein-coding genes on the Cryptococcus neoformans JEC21 genome. The genes presented here have been taken from INSDC records submitted by TIGR.

References

1. The genome of the basidiomycetous yeast and human pathogen Cryptococcus neoformans.
   Loftus BJ, Fung E, Roncaglia P, Rowley D, Amedeo P, Bruno D, Vamathevan J, Miranda M, Anderson IJ, Fraser JA et al. 2005. Science. 307:1321-1324.

More information

General information about this species can be found in Wikipedia.