Protein involved in regulation of sterol biosynthesis; specifically stabilizes Hmg2p, one of two HMG-CoA isoenzymes that catalyze the rate-limiting step in sterol biosynthesis; forms foci at the nuclear periphery upon DNA replication stress; relocalizes to the cytosol in response to hypoxia; homolog of mammalian INSIG proteins; NSG1 has a paralog, NSG2, that arose from the whole genome duplication [Source:SGD;Acc:S000001175]

Chromosome VIII: 370,722-371,597 reverse strand.

This transcript has 1 exon, is annotated with 11 domains and features, is associated with 23 variant alleles and maps to 29 oligo probes.

This transcript is a product of gene YHR133C Show transcript tableHide transcript table