GPI inositol deacylase of the endoplasmic reticulum (ER); negatively regulates COPII vesicle formation; prevents production of vesicles with defective subunits; required for proper discrimination between resident ER proteins and Golgi-bound cargo molecules; functional ortholog of human PGAP1, mutation of which is associated with intellectual disability and encephalopathy [Source:SGD;Acc:S000001869]
PER17
Chromosome VI: 84,145-87,234 reverse strand.
R64-1-1:BK006940.2
This gene has 1 transcript (splice variant) and 361 orthologues.