Nuclease subunit of the MRX complex with Rad50p and Xrs2p; complex functions in repair of DNA double-strand breaks and in telomere stability; Mre11p associates with Ser/Thr-rich ORFs in premeiotic phase; nuclease activity required for MRX function; widely conserved; forms nuclear foci upon DNA replication stress [Source:SGD;Acc:S000004837]
Chromosome XIII: 718,575-720,653 reverse strand.
This transcript has 1 exon, is annotated with 17 domains and features, is associated with 51 variant alleles and maps to 29 oligo probes.
This transcript is a product of gene YMR224C Show transcript tableHide transcript table
Name | Transcript ID | bp | Protein | Translation ID | Biotype | UniProt | RefSeq | Flags |
---|---|---|---|---|---|---|---|---|
MRE11 | YMR224C_mRNA | 2079 | 692aa | YMR224C | Protein coding | P32829 | - | Ensembl Canonical, |