DNA helicase, potent G-quadruplex DNA binder/unwinder; possesses strand annealing activity; promotes DNA synthesis during break-induced replication; important for crossover recombination; translation from different start sites produces mitochondrial and nuclear forms; nuclear form is a catalytic inhibitor of telomerase; mitochondrial form involved in DNA repair and recombination; mutations affect Zn, Fe homeostasis; regulated by Rad53p-dependent phosphorylation in rho0 cells [Source:SGD;Acc:S000004526]

Chromosome XIII: 148,953-151,532 reverse strand.

This transcript has 1 exon, is annotated with 16 domains and features, is associated with 48 variant alleles and maps to 29 oligo probes.

This transcript is a product of gene YML061C Show transcript tableHide transcript table