Transcriptional repressor that regulates hypoxic genes during normoxia; involved in the aerobic repression of genes such as COX5b, TIR1, and HEM13; binds DNA intrastrand cross-links formed by cisplatin; HMG (high mobility group box) domain containing protein which binds and bends cisplatin-modified DNA, blocking excision repair; IXR1 has a paralog, ABF2, that arose from the whole genome duplication [Source:SGD;Acc:S000001515]

Chromosome XI: 380,065-381,858 reverse strand.

This transcript has 1 exon, is annotated with 25 domains and features, is associated with 33 variant alleles and maps to 29 oligo probes.

This transcript is a product of gene YKL032C Show transcript tableHide transcript table