Endosomal subunit of membrane-associated retromer complex; required for retrograde transport; receptor that recognizes retrieval signals on cargo proteins, forms subcomplex with Vps26p and Vps29p that selects cargo proteins for retrieval; interacts with Ypt7p; overexpression of wild-type human VPS35 or Parkinson's-associated vps35-D686N or vps35-P299S variants complements Ni2+ resistance and Cd2+ sensitivity of yeast vps35 null mutant [Source:SGD;Acc:S000003690]

Chromosome X: 131,101-133,935 reverse strand.

This transcript has 1 exon, is annotated with 7 domains and features, is associated with 55 variant alleles and maps to 29 oligo probes.

This transcript is a product of gene YJL154C Show transcript tableHide transcript table