High affinity Ca2+/Mn2+ P-type ATPase; required for Ca2+ and Mn2+ transport into Golgi; involved in Ca2+ dependent protein sorting, processing; D53A mutant (Mn2+ transporting) is rapamycin sensitive, Q783A mutant (Ca2+ transporting) is rapamycin resistant; Mn2+ transport into Golgi lumen required for rapamycin sensitivity; mutations in human homolog ATP2C1 cause acantholytic skin condition Hailey-Hailey disease; human ATP2C1 can complement yeast null mutant [Source:SGD;Acc:S000003135]

Chromosome VII: 187,616-190,468 reverse strand.

This transcript has 1 exon, is annotated with 43 domains and features, is associated with 55 variant alleles and maps to 29 oligo probes.

This transcript is a product of gene YGL167C Show transcript tableHide transcript table