Saccharomyces cerevisiae (R64-1-1)
Description

Substrate-recruiting cofactor of the Cdc48p-Npl4p-Ufd1p segregase; assists Cdc48p in the dislocation of misfolded, polyubiquitinated ERAD substrates that are subsequently delivered to the proteasome for degradation; also involved in the regulated destruction of resident ER membrane proteins, such as HMG-CoA reductase (Hmg1/2p) and cytoplasmic proteins (Fbp1p); role in mobilizing membrane bound transcription factors by regulated ubiquitin/proteasome-dependent processing (RUP) [Source:SGD;Acc:S000000374]

Location
About this transcript

This transcript has 1 exon, is annotated with 10 domains and features, is associated with 28 variant alleles and maps to 29 oligo probes.

Gene

This transcript is a product of gene YBR170C Show transcript tableHide transcript table

NameTranscript IDbpProteinTranslation IDBiotypeUniProtRefSeqFlags
NPL4YBR170C_mRNA1743580aaYBR170C
 
Protein coding
P33755 -Ensembl Canonical
Statistics

Exons: 1, Coding exons: 1, Transcript length: 1,743 bps, Translation length: 580 residues

Uniprot

This transcript corresponds to the following Uniprot identifiers: P33755

Version

YBR170C_mRNA

Type

Protein coding

Annotation Method

Annotation imported from SGD