Ca2+-dependent cysteine protease; may cleave specific substrates during the stress response; regulates apoptosis upon H2O2 treatment; required for clearance of insoluble protein aggregates during normal growth; implicated in cell cycle dynamics and lifespan extension; undergoes autocatalytic processing; similar to mammalian metacaspases, but exists as a monomer due to an extra pair of anti-parallel beta-strands that block potential dimerization [Source:SGD;Acc:S000005723]
Chromosome XV: 717,086-718,384 forward strand.
This transcript has 1 exon, is annotated with 13 domains and features, is associated with 35 variant alleles and maps to 29 oligo probes.
This transcript is a product of gene YOR197W Show transcript tableHide transcript table
Name | Transcript ID | bp | Protein | Translation ID | Biotype | UniProt | RefSeq | Flags |
---|---|---|---|---|---|---|---|---|
MCA1 | YOR197W_mRNA | 1299 | 432aa | YOR197W | Protein coding | Q08601 | - | Ensembl Canonical, |