Molecular chaperone involved in protein folding in ER; mutation causes defects in cell wall synthesis and lysis of autophagic bodies, suppresses tor2 mutations, and is synthetically lethal with kar2-1 and with rot2 mutations; involved in N-linked glycosylation and O-mannosylation; transmembrane helix Ser250 is essential for Rot1p to interact with other membrane components and exert its functional role, avoiding exposure of Ser H-bonding group at lipid-exposed surface [Source:SGD;Acc:S000004813]

Chromosome XIII: 664,752-665,522 forward strand.

This transcript has 1 exon, is annotated with 8 domains and features, is associated with 15 variant alleles and maps to 29 oligo probes.

This transcript is a product of gene YMR200W Show transcript tableHide transcript table