Subunit of heterotrimeric Replication Protein A (RPA); RPA is a highly conserved single-stranded DNA binding protein complex involved in DNA replication, repair, recombination; RPA protects against inappropriate telomere recombination, and upon telomere uncapping, prevents cell proliferation by a checkpoint-independent pathway; with Sgs1p-Top2p-Rmi1p, stimulates DNA catenation/decatenation activity of Top3p; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000003709]

Chromosome X: 96,161-96,529 reverse strand.

This transcript has 1 exon, is annotated with 2 domains and features, is associated with 17 variant alleles and maps to 29 oligo probes.

This transcript is a product of gene YJL173C Show transcript tableHide transcript table