Component of the spindle-assembly checkpoint complex; delays onset of anaphase in cells with defects in mitotic spindle assembly; forms a complex with Mad1p; regulates APC/C activity during prometaphase and metaphase of meiosis I; gene dosage imbalance between MAD1 and MAD2 leads to chromosome instability [Source:SGD;Acc:S000003567]

Chromosome X: 387,657-388,247 forward strand.

This transcript has 1 exon, is annotated with 6 domains and features, is associated with 22 variant alleles and maps to 29 oligo probes.

This transcript is a product of gene YJL030W Show transcript tableHide transcript table