Component of RNA polymerase transcription factor TFIIH holoenzyme; acts as dsDNA-dependent translocase in context of TFIIH, unwinds DNA strands during initiation and promotes transcription start site (TSS) scanning; has DNA-dependent ATPase/helicase activity; interacts functionally with TFIIB, has roles in TSS selection and gene looping to juxtapose initiation and termination regions; involved in DNA repair; relocalizes to cytosol under hypoxia; homolog of human ERCC3 [Source:SGD;Acc:S000001405]

Chromosome IX: 80,510-83,041 reverse strand.

This transcript has 1 exon, is annotated with 33 domains and features, is associated with 49 variant alleles and maps to 29 oligo probes.

This transcript is a product of gene YIL143C Show transcript tableHide transcript table