Protein implicated in Mms22-dependent DNA repair during S phase; involved in recruiting the SMC5/6 complex to double-strand breaks; DNA damage induces phosphorylation by Mec1p at one or more SQ/TQ motifs; interacts with Mms22p and Slx4p; has four BRCT domains; has a role in regulation of Ty1 transposition; relative distribution to nuclear foci increases upon DNA replication stress [Source:SGD;Acc:S000001197]

Chromosome VIII: 402,966-406,178 forward strand.

This transcript has 1 exon, is annotated with 23 domains and features, is associated with 67 variant alleles and maps to 29 oligo probes.

This transcript is a product of gene YHR154W Show transcript tableHide transcript table