Endosomal protein involved in turnover of plasma membrane proteins; member of the DUP380 subfamily of conserved, often subtelomeric COS genes; required for the multivesicular vesicle body sorting pathway that internalizes plasma membrane proteins for degradation; Cos proteins provide ubiquitin in trans for nonubiquitinated cargo proteins [Source:SGD;Acc:S000003232]
Chromosome VII: 2,790-3,932 forward strand.
This transcript has 1 exon, is annotated with 5 domains and features, is associated with 36 variant alleles and maps to 29 oligo probes.
This transcript is a product of gene YGL263W Show transcript tableHide transcript table