NADPH oxidase localized to the perinuclear ER; produces superoxide from NADPH; overexpression causes MCA1 dependent apoptosis; likely involved in superoxide-mediated regulation of the actin cytoskeleton; member of a conserved superfamily of NADPH oxidases (NOX enzymes); has similarity to iron/copper reductases (FRE1-8), particularly Fre8p [Source:SGD;Acc:S000003128]
Chromosome VII: 200,561-202,273 forward strand.
This transcript has 1 exon, is annotated with 17 domains and features, is associated with 51 variant alleles and maps to 29 oligo probes.
This transcript is a product of gene YGL160W Show transcript tableHide transcript table