ER membrane protein that promotes export of misfolded polypeptides; required for ER-associated protein degradation of misfolded or unassembled proteins; initiates export of aberrant polypeptides from ER lumen by threading them into ER membrane and routing them to Hrd1p for ubiquitination; function normally requires N-terminal acetylation by NatB; N- and C- termini protrude into cytoplasm; similar to Dfm1p; homolog of mammalian derlin-1 [Source:SGD;Acc:S000000405]

Chromosome II: 623,576-624,211 forward strand.

This transcript has 1 exon, is annotated with 6 domains and features, is associated with 25 variant alleles and maps to 46 oligo probes.

This transcript is a product of gene YBR201W Show transcript tableHide transcript table