Subunit of phosphatidylinositol (PtdIns) 3-kinase complexes I and II; Complex I is essential in autophagy, Complex II is required for vacuolar protein sorting; required for overflow degradation of misfolded proteins when ERAD is saturated; C-terminus has novel globular fold essential for autophagy through the targeting of the PI3-kinase complex I to the pre-autophagosomal structure; ortholog of higher eukaryote gene Beclin 1; human BECN1 can complement yeast null mutant [Source:SGD;Acc:S000006041]

APG6, ATG6, VPT30

Chromosome XVI: 322,071-323,744 forward strand.

R64-1-1:BK006949.2

This gene has 1 transcript (splice variant), 336 orthologues and is a member of 1 Ensembl protein family.

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