Saccharomyces cerevisiae (R64-1-1)

Putative poly(U)-specific 3'-to-5' RNA exonuclease; involved in 3'-end processing of U6 snRNA removing uridines and generating a terminal 2′,3′ cyclic phosphate; essential protein that localizes to the nucleus and mitochondria; overexpression suppresses the respiratory defects of oxa1 and mtf2 mutants; homolog of S.pombe gene, mpn1 and human gene, hUSB1; mutations in hUSB1 are associated with a rare genodermatosis, poikiloderma with neutropenia (OMIM 604173) [Source:SGD;Acc:S000004122]


Chromosome XII: 407,283-408,155 reverse strand.


About this gene

This gene has 1 transcript (splice variant), 18 orthologues and is a member of 2 Ensembl protein families.

NameTranscript IDbpProteinTranslation IDBiotypeUniProtRefSeqFlags
Protein coding
Q12208 NM_001182019.1

Gene-based displays