Saccharomyces cerevisiae (R64-1-1)
Description

DNA replication initiation factor; recruited to MCM pre-RC complexes at replication origins; promotes release of MCM from Mcm10p, recruits elongation machinery; binds tightly to ssDNA, which disrupts interaction with the MCM helicase and stalls it during replication stress; mutants in human homolog may cause velocardiofacial and DiGeorge syndromes [Source:SGD;Acc:S000004093]

Synonyms

SLD4

Location

Chromosome XII: 343,989-345,941 reverse strand.

R64-1-1:BK006945.2

About this gene

This gene has 1 transcript (splice variant), 230 orthologues and is a member of 2 Ensembl protein families.

NameTranscript IDbpProteinTranslation IDBiotypeUniProtRefSeqFlags
CDC45YLR103C_mRNA1953650aaYLR103C
 
Protein coding
Q08032 NM_001181990.1
NP_013204.1

Gene-based displays