Saccharomyces cerevisiae (R64-1-1)
Description

Hexokinase isoenzyme 2; phosphorylates glucose in cytosol; predominant hexokinase during growth on glucose; represses expression of HXK1, GLK1, induces expression of its own gene; antiapoptotic; phosphorylation/dephosphorylation at Ser14 by kinase Snf1p, phosphatase Glc7p-Reg1p regulates nucleocytoplasmic shuttling of Hxk2p; functions downstream of Sit4p in control of cell cycle, mitochondrial function, oxidative stress resistance, chronological lifespan; has paralog HXK1 [Source:SGD;Acc:S000003222]

Synonyms

HEX1, HKB, SCI2

Location

Chromosome VII: 23,935-25,395 forward strand.

R64-1-1:BK006941.2

About this gene

This gene has 1 transcript (splice variant), 376 orthologues, 3 paralogues and is a member of 2 Ensembl protein families.

NameTranscript IDbpProteinTranslation IDBiotypeUniProtRefSeqFlags
HXK2YGL253W_mRNA1461486aaYGL253W
 
Protein coding
P04807 NM_001181119.1
NP_011261.1

Gene-based displays