G1 cyclin involved in regulation of the cell cycle; activates Cdc28p kinase to promote the G1 to S phase transition; late G1 specific expression depends on transcription factor complexes, MBF (Swi6p-Mbp1p) and SBF (Swi6p-Swi4p); CLN2 has a paralog, CLN1, that arose from the whole genome duplication; cell cycle arrest phenotype of the cln1 cln2 cln3 triple null mutant is complemented by any of human cyclins CCNA2, CCNB1, CCNC, CCND1, or CCNE1 [Source:SGD;Acc:S000006177]
Chromosome XVI: 64,977-66,614 reverse strand.
R64-1-1:BK006949.2
This gene has 1 transcript (splice variant), 341 orthologues and 8 paralogues.
Name | Transcript ID | bp | Protein | Translation ID | Biotype | UniProt | RefSeq | Flags |
---|---|---|---|---|---|---|---|---|
CLN2 | YPL256C_mRNA | 1638 | 545aa | YPL256C | Protein coding | P20438 | - | Ensembl Canonical, |