Component of the heterotetrameric MHF histone-fold complex; in humans the MHF complex interacts with both DNA and Mph1p ortholog FANCM, a Fanconi anemia complementation group protein, to stabilize and remodel blocked replication forks and repair damaged DNA; mhf1 srs2 double mutants are MMS hypersensitive; ortholog of human centromere constitutive-associated network (CCAN) subunit CENP-S, also known as MHF1 [Source:SGD;Acc:S000007626]
Chromosome XV: 159,173-159,445 forward strand.
R64-1-1:BK006948.2
This gene has 1 transcript (splice variant) and 15 orthologues.