Subunit of the inner nuclear membrane Asi ubiquitin ligase complex; the Asi complex targets both misfolded proteins of the inner nuclear membrane-associated degradation (INMAD) pathway and inner for ubiquitin-mediated degradation; acts with Asi1p and Asi3p to ensure the fidelity of SPS-sensor signaling by targeting latent unprocessed forms of Stp1p and Stp2p, maintaining the repressed state of gene expression in the absence of inducing amino acids [Source:SGD;Acc:S000005103]
Chromosome XIV: 338,478-339,347 reverse strand.
R64-1-1:BK006947.3
This gene has 1 transcript (splice variant) and 16 orthologues.
Name | Transcript ID | bp | Protein | Translation ID | Biotype | UniProt | RefSeq | Flags |
---|---|---|---|---|---|---|---|---|
ASI2 | YNL159C_mRNA | 870 | 289aa | YNL159C | Protein coding | P53895 | - | Ensembl Canonical, |