Protein involved in cytochrome c oxidase (Complex IV) assembly; involved in delivery of copper to Complex IV; also required for efficient formation of respiratory supercomplexes comprised of Complexes III and IV; localizes to the mitochondrial intermembrane space; ortholog implicated in cardiac defects in zebrafish and human; transcription is induced in response to the DNA-damaging agent MMS; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000004857]

Chromosome XIII: 758,517-758,831 reverse strand.

R64-1-1:BK006946.2

This gene has 1 transcript (splice variant) and 121 orthologues.

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