Beta subunit of the translation initiation factor eIF2B; the guanine-nucleotide exchange factor for eIF2; activity subsequently regulated by phosphorylated eIF2; first identified as a negative regulator of GCN4 expression; human homolog EIF2B2 can complement yeast mutant, allows growth down-regulation of yeast gene [Source:SGD;Acc:S000004282]
Chromosome XII: 718,317-719,462 reverse strand.
R64-1-1:BK006945.2
This gene has 1 transcript (splice variant), 339 orthologues and 3 paralogues.