EH domain-containing protein; involved in regulating phosphatidylinositol 4,5-bisphosphate levels and autophagy; Irs4p and Tax4p bind and activate the PtdIns phosphatase Inp51p; Irs4p and Tax4p are involved in localizing Atg17p to the PAS; IRS4 has a paralog, TAX4, that arose from the whole genome duplication [Source:SGD;Acc:S000001727]
Chromosome XI: 476,216-478,063 reverse strand.
R64-1-1:BK006944.2
This gene has 1 transcript (splice variant), 90 orthologues and 5 paralogues.