Subunit of the DSC ubiquitin ligase complex; golgi-localized RING-finger ubiquitin ligase (E3) involved in sorting polar transmembrane domain containing membrane proteins to multivesicular bodies for delivery to the vacuole; proposed involvement in the quality control of misfolded TMD containing proteins; ortholog of fission yeast dsc1 [Source:SGD;Acc:S000001517]

Chromosome XI: 371,829-374,105 forward strand.

R64-1-1:BK006944.2

This gene has 1 transcript (splice variant) and 29 orthologues.

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