Fumarate reductase, catalyzes the reduction of fumarate to succinate; required for the reoxidation of intracellular NADH under anaerobic conditions; mutations cause osmotic sensitivity; has two translation start sites, one at the annotated start codon which produces an ER-targeted form required for anaerobic growth, and one at codon 32 which produces a mitochondrially-targeted form; OSM1 has a paralog, FRD1, that arose from the whole genome duplication [Source:SGD;Acc:S000003812]

FRDS2

Chromosome X: 529,861-531,366 forward strand.

R64-1-1:BK006943.2

This gene has 1 transcript (splice variant), 250 orthologues and 3 paralogues.

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