DNA helicase and DNA-dependent ATPase; involved in DNA repair and checkpoint recovery, needed for proper timing of commitment to meiotic recombination and transition from Meiosis I to II; blocks trinucleotide repeat expansion; affects genome stability; disassembles Rad51p nucleoprotein filaments during meiotic recombination; stimulates activity of the Mus81p-Mms4p endonuclease, independently of Srs2p catalytic activity; functional homolog of human RTEL1 [Source:SGD;Acc:S000003628]
HPR5, RADH, RADH1
Chromosome X: 257,423-260,947 forward strand.
R64-1-1:BK006943.2
This gene has 1 transcript (splice variant), 324 orthologues and 1 paralogue.