Part of actin cytoskeleton-regulatory complex Pan1p-Sla1p-End3p; associates with actin patches on cell cortex; promotes protein-protein interactions essential for endocytosis; binds to and activates Arp2/3 complex in vitro; phosphorylation of Thr-1225 is regulated by MAPK Hog1p in response to osmotic stress; previously thought to be a subunit of poly(A) ribonuclease [Source:SGD;Acc:S000001445]
DIM2, MDP3, MIP3
Chromosome IX: 365,466-369,908 reverse strand.
R64-1-1:BK006942.2
This gene has 1 transcript (splice variant), 284 orthologues and 5 paralogues.