ER quality-control lectin; integral subunit of the HRD ligase; participates in efficient ER retention of misfolded proteins by recognizing them and delivering them to Hrd1p; binds to glycans with terminal alpha-1,6 linked mannose on misfolded N-glycosylated proteins and participates in targeting proteins to ERAD; member of the OS-9 protein family [Source:SGD;Acc:S000002464]
Chromosome IV: 565,927-567,555 forward strand.
R64-1-1:BK006938.2
This gene has 1 transcript (splice variant) and 14 orthologues.