Candida albicans GC75 (Cand_albi_GC75_V1)

Candida albicans GC75 Assembly and Gene Annotation

About Candida albicans GC75

Wikipedia

Candida albicans is a dimorphic fungus that grows both as yeast and filamentous cells and one of the few species of the Candida genus that cause the infection candidiasis in humans. C. albicans is responsible for 50–90% of all cases of candidiasis in humans. Systemic fungal infections (fungemias) including those by C. albicans have emerged as important causes of morbidity and mortality in immunocompromised patients (e.g., AIDS, cancer chemotherapy, organ or bone marrow transplantation). C. albicans biofilms may form on the surface of implantable medical devices. In addition, hospital-acquired infections by C. albicans have become a cause of major health concerns. About 85-95% of vaginal infections cases are responsible for physician office visits every year. Overgrowth of the fungus results in candidiasis (candidosis). Candidiasis is often observed in immunocompromised individuals, including HIV-infected patients. It commonly occurs on mucous membranes in the mouth or vagina, but may affect a number of other regions. For example, higher prevalence of colonization of C. albicans was reported in young individuals with tongue piercing, in comparison to unpierced matched individuals. To infect host tissue, the usual unicellular yeast-like form of C. albicans reacts to environmental cues and switches into an invasive, multicellular filamentous form, a phenomenon called dimorphism. In addition, an overgrowth infection is considered superinfection, usually applied when an infection become opportunistic and very resistant to antifungals. It then becomes suppressed by antibiotics. The infection is prolonged when the original sensitive strain is replaced by the antibiotic-resistant strain.

(Text and image from Wikipedia, the free encyclopaedia.)

Assembly

The assembly presented is the Cand_albi_GC75_V1 assembly submitted to INSDC with the assembly accession GCA_000773735.1.

Annotation

The annotation presented is derived from annotation submitted to INSDC with the assembly accession GCA_000773735.1, with additional non-coding genes derived from Rfam. For more details, please visit INSDC annotation import.

More information

General information about this species can be found in Wikipedia.

Statistics

Summary

AssemblyCand_albi_GC75_V1, INSDC Assembly GCA_000773735.1, Nov 2014
Database version92.1
Base Pairs14,696,915
Golden Path Length14,696,915
Genebuild byENA
Genebuild methodGenerated from ENA annotation
Data sourceEuropean Nucleotide Archive

Gene counts

Coding genes6,310
Non coding genes278
Small non coding genes278
Gene transcripts6,588

About this species